Title :
Surface acoustic wave resonators as novel tools for multiparametric blood analysis
Author :
Guhr, G. ; Brünig, R. ; Schmidt, H. ; Weihnacht, M. ; Gehrisch, S. ; Siegert, G.
Author_Institution :
IFW Dresden, Dresden, Germany
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
In this paper a new tool to assess viscoelastic and dielectric properties of human fluids is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of coagulating blood and blood plasma samples. One-port SAW resonators, with fundamental modes of 85, 170 und 340 MHz were developed. Additionally, their electrode structures can be used simultaneously to detect the dielectric behavior of the whole system by impedance spectroscopy while the frequency ranges from kHz to MHz. The combination of both methods offers the detection of clinical relevant blood parameters like the blood coagulation time and the hematocrit value within one measurement.
Keywords :
biomedical electrodes; biomedical measurement; blood; coagulation; dielectric properties; haemodynamics; surface acoustic wave resonators; viscoelasticity; blood coagulation time; blood plasma samples; dielectric properties; electrode structures; hematocrit value; human fluids; impedance spectroscopy; multiparametric blood analysis; one-port SAW resonators; shear horizontal polarized surface acoustic waves; surface acoustic wave resonators; viscoelastic properties; Coagulation; Impedance; Plasmas; Resonant frequency; Surface acoustic waves; Surface impedance; Acoustics; Biosensing Techniques; Blood Chemical Analysis; Complex Mixtures; Equipment Design; Equipment Failure Analysis; Micro-Electrical-Mechanical Systems;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5627792
