DocumentCode :
2954570
Title :
Statistical Classification and Visualization of MALDI-Imaging Data
Author :
Gerhard, Marc ; Deininger, Sören-Oliver ; Schleif, Frank-Michael
Author_Institution :
Bruker Daltonik GmbH, Bremen
fYear :
2007
fDate :
20-22 June 2007
Firstpage :
403
Lastpage :
405
Abstract :
Proteomic profiling based on mass spectrometry (ms) is an important tool for studies at the protein and peptide level. Thereby, the identification of relevant masses for a specific kind of disease, discriminating classification models as well as a reliable visualization is complicated. For the analysis of tissue sections the new technique of MALDI-Imaging has been introduced, which results in new data analysis challenges. Here we present a method for the analysis and visualization of MALDI Imaging spectra applied on a clinical cancer data set.
Keywords :
cancer; image classification; laser applications in medicine; mass spectroscopy; medical image processing; molecular biophysics; photoionisation; photon stimulated desorption; proteins; tumours; MALDI imaging; clinical cancer data set; data visualization; disease; mass spectrometry; peptide; protein; proteomic profiling; statistical classification; tissue sections; Cancer; Data analysis; Data visualization; Image analysis; Mass spectroscopy; Packaging; Principal component analysis; Proteomics; Support vector machine classification; Support vector machines; class imaging; clinical proteomics; data analysis; maldi imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computer-Based Medical Systems, 2007. CBMS '07. Twentieth IEEE International Symposium on
Conference_Location :
Maribor
ISSN :
1063-7125
Print_ISBN :
0-7695-2905-4
Type :
conf
DOI :
10.1109/CBMS.2007.99
Filename :
4262682
Link To Document :
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