Title :
Extreme Learning Machine based bacterial protein subcellular localization prediction
Author :
Lan, Yuan ; Soh, Yeng Chai ; Huang, Guang-Bin
Author_Institution :
Sch. of Electr. & Electron. Eng., Nanyang Technol. Univ., Singapore
Abstract :
In this paper, extreme learning machine (ELM) is introduced to predict the subcellular localization of proteins based on the frequent subsequences. It is proved that ELM is extremely fast and can provide good generalization performance. We evaluated the performance of ELM on four localization sites with frequent subsequences as the feature space. A new parameter called Comparesup was introduced to help the feature selection. The performance of ELM was tested on data with different number of frequent subsequences, which were determined by different range of Comparesup. The results demonstrated that ELM performed better than previously reported results, for all of the four localization sites.
Keywords :
biology computing; cellular biophysics; learning (artificial intelligence); microorganisms; prediction theory; proteins; Comparesup; bacterial protein subcellular localization; extreme learning machine; feature selection; prediction; Machine learning; Microorganisms; Neural networks; Proteins;
Conference_Titel :
Neural Networks, 2008. IJCNN 2008. (IEEE World Congress on Computational Intelligence). IEEE International Joint Conference on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-1820-6
Electronic_ISBN :
1098-7576
DOI :
10.1109/IJCNN.2008.4634051