Title :
Baroreflex contribution to linear and nonlinear blood pressure and heart rate coupling in daily life: an assessment by cross-mutual information
Author :
Rienzo, M. Di ; Castiglioni, P. ; Parati, G. ; Zwiener, U. ; Pompe, B. ; Hoyer, D.
Author_Institution :
Centro di Bioingegneria, Fnd Don C Gnocchi & Politecnico, Milano, Italy
Abstract :
A new procedure has been developed to (1) investigate the coupling between arterial blood pressure and heart rate variability in daily life and (2) identify the baroreflex contribution to such a coupling. The algorithm is based on the estimation of cross-mutual information (CMI) between systolic blood pressure (SBP) and RR-interval (RRI) beat-to-beat values. CMI has been selected because of its capability to quantify both linear and nonlinear components of the coupling between variables. This procedure has been used to analyze data recorded in spontaneously behaving cats before and seven days after surgical opening of the baroreflex loop as obtained by a sino-aortic denervation. Use of CMI indicates that over a time scale on the order of minutes the arterial baroreflex is the major determinant of the SBI-RRI link, accounting for about 2/3 of the total (linear and nonlinear) coupling measured between these variables.
Keywords :
cardiovascular system; medical signal processing; RR-interval beat-to-beat values; arterial baroreflex; arterial blood pressure; baroreflex contribution; cross-mutual information; daily life; heart rate variability; sino-aortic denervation; spontaneously behaving cats; surgical baroreflex loop opening; systolic blood pressure; Arterial blood pressure; Baroreflex; Blood pressure; Cats; Couplings; Data analysis; Heart rate; Heart rate variability; Rail to rail inputs; Surgery;
Conference_Titel :
Computers in Cardiology, 2002
Print_ISBN :
0-7803-7735-4
DOI :
10.1109/CIC.2002.1166706