DocumentCode :
2967938
Title :
The response of intact guinea pigs to AC leakage currents
Author :
Patel, S. ; Malkin, RA
Author_Institution :
Memphis Univ., TN, USA
fYear :
2002
fDate :
22-25 Sept. 2002
Firstpage :
729
Lastpage :
731
Abstract :
There was a difference in the standard for leakage current in the US and Europe. This difference existed largely because there was very little data on AC stimulation of the heart in situ. In this study, we examine AC stimulation of the intact guinea pig. Nine male guinea pigs were anesthetized with isoflurane, intubated and monitored with the lead II ECG and optical plethysmograph. For AC stimulation, a stainless steel electrode was used The return electrode was applied to the right rear paw. Five seconds of AC stimuli at various frequencies was used The minimum VF threshold in these animals was found to be 558±314 μA at 100 Hz. Frequencies both below (20 Hz: 1584±753 μA) and above (160 Hz: 1355±1007 pA) were found to be significantly different from 100 Hz (20 Hz: p=0.0017 and 100 Hz: p=0.0085). By contrast the minimum current required to have any effect on the heart only increased with frequency from 10 Hz (119±53 pA), to 160 Hz (183±50 pA, p<0. 0001).
Keywords :
electrocardiography; plethysmography; AC stimulation; intact guinea pig; isoflurane; lead H ECG; leakage current; optical plethysmograph; stainless steel electrode; Electrocardiography; Electrodes; Europe; Frequency; Heart; Leakage current; Monitoring; Plasma welding; Steel; Stimulated emission;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computers in Cardiology, 2002
ISSN :
0276-6547
Print_ISBN :
0-7803-7735-4
Type :
conf
DOI :
10.1109/CIC.2002.1166876
Filename :
1166876
Link To Document :
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