Title :
Computational analysis of PTEN-targeting microRNAs
Author :
Hew, Soon-Hin ; Tee, Sim-Hui
Author_Institution :
Multimedia Univ., Cyberjaya, Malaysia
Abstract :
Computational tools are indispensable in the genetic engineering today. This research employs computational analysis on microRNAs which are targeting at the PTEN gene. This study aims to analyze the implication of microRNAs in the expression of PTEN which is leading to tumorigenesis. The analysis of microRNAs sheds light on the regulatory mechanism of PTEN in cancer development.
Keywords :
RNA; biochemistry; bioinformatics; cancer; enzymes; genetic engineering; genetics; medical computing; molecular biophysics; tumours; PTEN gene expression; PTEN-targeting microRNA; cancer development; computational analysis; genetic engineering; phosphatase and tensin homolog; tumorigenesis; Cancer; Databases; Gene expression; Genetic engineering; Humans; RNA; Tumors; PTEN; bioinformatics; genetic engineering; microRNA;
Conference_Titel :
Humanities, Science and Engineering Research (SHUSER), 2012 IEEE Symposium on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4673-1311-7
DOI :
10.1109/SHUSER.2012.6268782
