Title :
Magnetically-actuated blood filter for a CMOS-based nanowire biosensor
Author :
Chung, Kwang Hyo ; Ahn, Chang-Geun ; Choi, Yo Han ; Yang, Jong-Heon ; Park, Chan Woo ; Kim, Wan-Joong ; Ah, Chil Seong ; Sung, Gun Yong
Author_Institution :
Biosensor Res. Team, Electron. & Telecommun. Res. Inst.(ETRI), Daejeon, South Korea
Abstract :
We present a novel blood filter device which is actuated by simple magnetic squeezing to layered membranes. The filter gives a good performance in high plasma recovery yield (~25%), nearly-perfect filtering efficiency (~100%), low blood consumption (<;50μl), fast operation (<;1 min.). Performance of the filter was tested for various geometrical and operational parameters. The filter is designed for disposable and versatile usage, and it is applied to a CMOS FET-based nanowire biosensor.
Keywords :
biosensors; nanowires; CMOS-based nanowire biosensor; magnetic squeezing; magnetically-actuated blood filter; Biomembranes; Blood; Cells (biology); Magnetic separation; Microfluidics; Permanent magnets; Plasmas;
Conference_Titel :
Sensors, 2011 IEEE
Conference_Location :
Limerick
Print_ISBN :
978-1-4244-9290-9
DOI :
10.1109/ICSENS.2011.6127337