In silico prediction of MicroRNA´s from chromosome no, 1 & 2 of Plasmodium vivax

MicroRNAs (MiRNA´s) are ~22nt long; one of the types of non-coding RNA having an important role in the control of the gene regulation, either by termination of the translation procedure or sometimes activating the gene actively or passively. Host-Parasite relationship largely depends on the gene regulatory network as the parasite has to survive in the host cell against the immune response of the host. So miRNA may have an important role in the host parasite relationship. The malarial parasite needs to survive in the human host cell during its life cycle. As it is well known to us today that the gene regulatory network is largely controlled by the non coding miRNA, here we are interested to find out potential miRNA in the parasite genome computationally. We have identified few putative miRNA genes in the chromosome 1 & 2 of Plasmodium vivax which need to be validated by experimental procedures.