Low-power amplifier for in-vivo EEG signal recording

There is an increasing demand for more advanced and effective medical devices due to the interest on real-time personal home health monitoring. The electroencephalogram (EEG) is a common noninvasive method for various applications, such as the prediction of epileptic seizure and brain-computer interfaces (BCIs). A key component of an EEG monitoring systems is the acquisition circuitry with ultra low-power dissipation. This paper presents the implementation of an EEG signal amplifier. The presented amplifier has been designed and simulated in 90nm 1P9M CMOS technology, consumes 3.6 μW from a 1.2 V supply voltage and occupies an active area of 0.048 mm². The bandwidth widens from a low-frequency cutoff of below 0.1 Hz to a high-frequency cutoff of 10 kHz which is suitable for EEG signals. The amplifier is simulated using the real EEG signal recorded using EEG-1100 machine in Emam Reza hospital.