Title :
Iontophoretic drug delivery models
Author :
Pang, G.K.H. ; Qiao, Dapeng
Author_Institution :
Dept. of Electr. & Electron. Eng., Univ. of Hong Kong, Hong Kong, China
Abstract :
Iontophoresis relies on active transportation of the charged medication agent within an electric field and delivers medication transdermally. It uses electric current to ionize drug molecules and propel them through the skin. It is a kind of transdermal drug delivery method, and hence the method has to handle the variability in skin characteristics of a patient. In this paper, a preliminary study based on the different models of the skin impedance is carried out. The purpose is to examine several skin models for iontophoretic drug delivery. This paper carries out a simulation study based on three different skin impedance models.
Keywords :
bioelectric phenomena; drug delivery systems; physiological models; skin; iontophoretic drug delivery models; skin impedance models; Capacitors; Drug delivery; Drugs; Epidermis; Impedance; Integrated circuit modeling; Non-invasive drug delivery; electrically-assisted delivery; iontophoresis; skin impedance;
Conference_Titel :
Biomedical Engineering (MECBME), 2011 1st Middle East Conference on
Conference_Location :
Sharjah
Print_ISBN :
978-1-4244-6998-7
DOI :
10.1109/MECBME.2011.5752133