Title :
Airway Smooth Muscle Mechanics, Remodeling and Proliferation: Effects of Aicar and Metformin
Author :
Ratnovsky, Anat ; An, Steven S. ; Mellema, Mathew ; Fredberg, Jeffrey J. ; Shore, Stephanie A.
Author_Institution :
Dept. of Environ. Health, Harvard Sch. of Public Health, Boston, MA
Abstract :
Obesity is a risk factor for asthma. The purpose of this study was to determine whether metformin, an agent used in the treatment of another obesity-related condition, type II diabetes, might have therapeutic potential for airway smooth muscle (ASM) function in obesity.
Keywords :
biomechanics; diseases; health care; medical computing; AICAR; airway smooth muscle mechanics; asthma; metformin; obesity; risk factor; type II diabetes; Cancer; Cells (biology); Diabetes; Magnetic fields; Mechanical factors; Mechanical variables measurement; Microscopy; Muscles; Optical sensors; Public healthcare; ASM cell; Asthma; Mechanics; Obesity; Proliferation;
Conference_Titel :
Information Technology: Research and Education, 2006. ITRE '06. International Conference on
Conference_Location :
Tel-Aviv
Print_ISBN :
1-4244-0858-X
Electronic_ISBN :
1-4244-0859-8
DOI :
10.1109/ITRE.2006.381532
