Title :
Localization of Hot Spots in Proteins Using Digital Filters
Author :
Ramachandran, Parameswaran ; Antoniou, Andreas
Author_Institution :
Dept. of Electr. & Comput. Eng., Victoria Univ., BC
Abstract :
A new technique of using digital filters for identifying the locations of hot spots in proteins is proposed. The technique involves the design of a special digital filter that would select the characteristic frequency of interest. The energy of the filter output yields the locations of the hot spots. The new technique is as accurate as a transform-based technique but requires considerably less computation due to the use of a low-order IIR filter for the necessary processing
Keywords :
IIR filters; biology computing; proteins; transforms; characteristic frequency; digital filters; low-order IIR filter; protein hot spot localization; transform-based technique; Amino acids; Biological system modeling; Character recognition; Charge carrier processes; Digital filters; Digital signal processing; Frequency; IIR filters; Protein engineering; Resonance; Proteins; characteristic frequency; digital filters; electron-ion interaction potential (EIIP); hot spots; resonant recognition model (RRM);
Conference_Titel :
Signal Processing and Information Technology, 2006 IEEE International Symposium on
Conference_Location :
Vancouver, BC
Print_ISBN :
0-7803-9753-3
Electronic_ISBN :
0-7803-9754-1
DOI :
10.1109/ISSPIT.2006.270930
