Title :
Bioconjugated Au/Ag nanocages as a novel optical imaging contrast and thermal therapeutic agent
Author :
Chen, Jingyi ; Saeki, Fusayo ; Wiley, Benjamin J. ; Cang, Hu ; Au, Leslie ; Zhang, Hui ; Cobb, Michael J. ; Kimmey, Michael B. ; Xia, Younan ; Li, Xingde
Author_Institution :
Dept. of Chem., Washington Univ., Seattle, WA, USA
Abstract :
We have synthesized 40-nm Au/Ag nanocages and explored their use as an optical imaging/spectroscopy contrast agent and potentially a thermal therapeutic agent. Cancer cell specific targeting by antibody-conjugated nanocages has also been demonstrated.
Keywords :
biomedical optical imaging; biothermics; cancer; cellular biophysics; gold alloys; nanostructured materials; nanotechnology; patient treatment; silver alloys; 40 nm; AuAg; antibody-conjugated nanocages; bioconjugated Au/Ag nanocages; cancer cell specific targeting; optical imaging contrast agent; optical spectroscopy; thermal therapeutic agent; Biomedical imaging; Biomedical optical imaging; Gold; Imaging phantoms; Nanobioscience; Nanoparticles; Optical imaging; Optical scattering; Optical sensors; Silver;
Conference_Titel :
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN :
1-55752-795-4
DOI :
10.1109/CLEO.2005.202365
