Title :
Single cell detection using a microfluidic, passive, Fabry-Perot interferometer based biosensor
Author :
Shao, Hua ; Kumar, Dhiraj ; Lear, Kevin L.
Author_Institution :
Dept. of Electr. & Comput. Eng., Colorado State Univ., Fort Collins, CO, USA
Abstract :
Polystyrene spheres, yeast cells, and blood cells in a microfluidic Fabry-Perot cavity constructed using thermocompressive gold bonding show unique transmission spectra that can be used for differentiation and are approximately consistent with modeling results.
Keywords :
Fabry-Perot interferometers; bio-optics; biomedical equipment; blood; cellular biophysics; light transmission; microfluidics; polymers; biosensor; blood cells; microfluidic Fabry-Perot cavity; passive microfluidic Fabry-Perot interferometer; polystyrene spheres; single cell detection; thermocompressive gold bonding; transmission spectra; yeast cells; Biomedical measurements; Biosensors; Cells (biology); Fabry-Perot interferometers; Fungi; Light emitting diodes; Microfluidics; Mirrors; Scanning electron microscopy; Spectroscopy;
Conference_Titel :
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN :
1-55752-795-4
DOI :
10.1109/CLEO.2005.202399