DocumentCode
2988085
Title
Miniature fluorescent metabolometer
Author
Ao, Tao ; Zhou, Lanlan ; Chance, Britton
Author_Institution
Dept. of Biophys. & Biochem., Pennsylvania Univ., Philadelphia, PA, USA
Volume
3
fYear
2005
fDate
22-27 May 2005
Firstpage
2230
Abstract
The authors describe a non-intrusive method for monitoring the fluorescent reduced nicotinamide adenine dinucleotide (NADH) and the reduced flavin adenine dinucleotide (FADH2) fluorescence intensities. The ratio of the fluorescence intensities gives a measure of the oxidation-reduction (redox) state of the tissue. A yeast model has been established to calibrate the instrument.
Keywords
bio-optics; biochemistry; biological techniques; biological tissues; bolometers; calibration; enzymes; fluorescence; molecular biophysics; oxidation; reduction (chemical); calibration; flavin adenine dinucleotide; fluorescence intensities; fluorescent reduced nicotinamide adenine dinucleotide; miniature fluorescent metabolometer; nonintrusive method; oxidation-reduction state; tissue; yeast; Biomedical optical imaging; Fluorescence; Fungi; Humans; Instruments; Laboratories; Light emitting diodes; Monitoring; Probes; Signal processing;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN
1-55752-795-4
Type
conf
DOI
10.1109/CLEO.2005.202426
Filename
1573492
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