• DocumentCode
    2988482
  • Title

    Laser-assisted controlled micro-injection into living cells

  • Author

    Peng, Cheng ; Wilke, Ingrid ; Palazzo, Robert E.

  • Author_Institution
    Dept. of Phys., Rensselaer Polytech. Inst., Troy, NY, USA
  • Volume
    3
  • fYear
    2005
  • fDate
    22-27 May 2005
  • Firstpage
    2305
  • Abstract
    A titanium-sapphire laser emitting 100 fs short laser pulses at 800 nm wavelength is employed to inject an impermeable dye into single living cells. The cell morphology remains intact after this process. A new method to analyze dye uptake and evaluate membrane integrity is suggested.
  • Keywords
    biomembranes; cellular biophysics; dyes; high-speed optical techniques; laser applications in medicine; solid lasers; titanium; 100 fs; 800 nm; Al2O3:Ti; cell morphology; dye uptake; impermeable dye; laser-assisted controlled micro-injection; living cells; membrane integrity; short laser pulses; titanium-sapphire laser; Biomedical optical imaging; Biomembranes; Cells (biology); Fluorescence; Laser theory; Microinjection; Optical control; Optical microscopy; Optical pulses; Ultrafast optics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics, 2005. (CLEO). Conference on
  • Print_ISBN
    1-55752-795-4
  • Type

    conf

  • DOI
    10.1109/CLEO.2005.202452
  • Filename
    1573518