DocumentCode
2988527
Title
Nanometer axial position sensing in optical tweezers using differential confocal microscopy
Author
Kuo, Kai-Wen ; Xiao, Jian-Long ; Lee, Chau-Hwang
Author_Institution
Inst. of Biophotonics Eng., Nat. Yang-Ming Univ., Taipei, Taiwan
Volume
3
fYear
2005
fDate
22-27 May 2005
Firstpage
2314
Abstract
We use differential confocal microscopy for axial detection in optical tweezers. The fluctuation of a 3 μm bead is about 10 nm at 16 mW. This technique is employed for studying protein elasticity and microrheology.
Keywords
biological techniques; biomechanics; biorheology; elasticity; molecular biophysics; optical microscopy; proteins; radiation pressure; bead fluctuation; differential confocal microscopy; microrheology; nanometer axial position sensing; optical tweezers; protein elasticity; Biomedical optical imaging; Fluctuations; Fluorescence; Laser beams; Lasers and electrooptics; Optical microscopy; Optical scattering; Optical sensors; Proteins; Semiconductor lasers;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN
1-55752-795-4
Type
conf
DOI
10.1109/CLEO.2005.202455
Filename
1573521
Link To Document