Title :
Follow-up computerized study of Clozaril therapy
Author :
Ortiz, M.T. ; Kozma, K.E.
Author_Institution :
NYS Inst. for Basic Res. in Dev. Disabilities, Staten Island, NY, USA
Abstract :
The primary harmful side effect of Clozaril, an antipsychotic agent, is agranulocytosis. An established computerized database was modified and improved to monitor Clozaril patients in New York State Psychiatric Centers. Six centers with a total of 241 patients were monitored from 6/1/1991 to 9/30/1992. White blood cell test results were recorded for each patient. Thirteen patients were found to exhibit signs of agranulocytosis. The pattern of results for each of the 13 patients was examined, indicating that sound courses of action were subsequently taken. Further work is planned to include continued monitoring and age and/or sex based studies
Keywords :
blood; cellular biophysics; computerised monitoring; medical computing; patient monitoring; patient treatment; relational databases; Clozapine; Clozaril therapy; MUMPS; RDBMS; agranulocytosis; antipsychotic agent; computerized database; computerized monitoring; continued monitoring; follow-up computerised study; harmful side effect; white blood cell counts; Computerized monitoring; Condition monitoring; Data mining; Demography; Drugs; Laboratories; Medical treatment; Patient monitoring; Psychology; Testing;
Conference_Titel :
Bioengineering Conference, 1993., Proceedings of the 1993 IEEE Nineteenth Annual Northeast
Conference_Location :
Newark, NJ
Print_ISBN :
0-7803-0925-1
DOI :
10.1109/NEBC.1993.404357
