Title :
Possible explanations for tonometric variation of brain death model in swine
Author :
Merris, Mark ; Nain, Sheela H. ; Sarma, Lalitha ; LaCourse, John ; Selikowitz, Stuart
Author_Institution :
Dept. of Biomed. Eng., New Hampshire Univ., Durham, NH, USA
Abstract :
The use of two miniature pigs as a model system to evaluate the use of tonometry for non-invasive monitoring of cerebral blood flow for the determination of brain death is discussed. Normal values of tonometric measurement were determined and plotted during experimentation. Brain death was simulated by sequentially occluding the arterial blood supply to the brain. Tonometric readings illustrated variations in intraocular pressure. Hypothetical theories are offered to systematically explain the differences and direct future research
Keywords :
bioelectric potentials; brain; eye; haemodynamics; physiological models; brain death model; cerebral blood flow; intraocular pressure; miniature pigs; noninvasive monitoring; swine; tonometric variation; Angiography; Animals; Biomedical engineering; Biomedical measurements; Blood flow; Brain modeling; Coaxial cables; Drugs; Electrocardiography; Electroencephalography;
Conference_Titel :
Bioengineering Conference, 1993., Proceedings of the 1993 IEEE Nineteenth Annual Northeast
Conference_Location :
Newark, NJ
Print_ISBN :
0-7803-0925-1
DOI :
10.1109/NEBC.1993.404402
