A multicompartmental model for simulation of soluble gas exchange in the lungs

Author

Ritter, Arthur ; Varadhan, Chitra ; Kristol, David

Author_Institution

Dept. of Physiol., New Jersey Med. Sch., Newark, NJ, USA

fYear

1993

fDate

18-19 Mar 1993

Firstpage

80

Lastpage

81

Abstract

A lung model for soluble gas exchange that will allow quantitative estimation of the pharmacokinetics of inhaled anesthetic agents is described. This lung model is coupled to a whole body hemodynamic model given by B. Pu´ramic (M.S. thesis, New Jersey Inst. of Techn., 1992). The partial pressure of a soluble gas in the pulmonary artery (PPA), the integrated average pulmonary capillary pressure (PPC), and the partial pressure of gas in the pulmonary vein (PPV) system for one set of simulation values are shown. The partial pressures of the gas in the three lung capillary zones are also given

Keywords

biology computing; haemodynamics; lung; physiological models; pneumodynamics; TUTSIM; blood-tissue exchange; inhaled anesthetic agents; integrated average pulmonary capillary pressure; lung model; multicompartmental model; partial pressure; pharmacokinetics; pulmonary artery; pulmonary mechanics; quantitative estimation; respiration regulation; simulation; soluble gas exchange; transport function; whole body hemodynamic model; Arteries; Biochemistry; Biomedical engineering; Blood; Computational modeling; Equations; Lungs; Medical simulation; Physiology; Veins;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1993., Proceedings of the 1993 IEEE Nineteenth Annual Northeast

Conference_Location

Newark, NJ

Print_ISBN

0-7803-0925-1

Type

conf

DOI

10.1109/NEBC.1993.404407

Filename

404407