Title :
A multicompartmental model for simulation of soluble gas exchange in the lungs
Author :
Ritter, Arthur ; Varadhan, Chitra ; Kristol, David
Author_Institution :
Dept. of Physiol., New Jersey Med. Sch., Newark, NJ, USA
Abstract :
A lung model for soluble gas exchange that will allow quantitative estimation of the pharmacokinetics of inhaled anesthetic agents is described. This lung model is coupled to a whole body hemodynamic model given by B. Pu´ramic (M.S. thesis, New Jersey Inst. of Techn., 1992). The partial pressure of a soluble gas in the pulmonary artery (PPA), the integrated average pulmonary capillary pressure (PPC), and the partial pressure of gas in the pulmonary vein (PPV) system for one set of simulation values are shown. The partial pressures of the gas in the three lung capillary zones are also given
Keywords :
biology computing; haemodynamics; lung; physiological models; pneumodynamics; TUTSIM; blood-tissue exchange; inhaled anesthetic agents; integrated average pulmonary capillary pressure; lung model; multicompartmental model; partial pressure; pharmacokinetics; pulmonary artery; pulmonary mechanics; quantitative estimation; respiration regulation; simulation; soluble gas exchange; transport function; whole body hemodynamic model; Arteries; Biochemistry; Biomedical engineering; Blood; Computational modeling; Equations; Lungs; Medical simulation; Physiology; Veins;
Conference_Titel :
Bioengineering Conference, 1993., Proceedings of the 1993 IEEE Nineteenth Annual Northeast
Conference_Location :
Newark, NJ
Print_ISBN :
0-7803-0925-1
DOI :
10.1109/NEBC.1993.404407
