Title :
Molecular Imaging of EGFR Expression in Live Cancer Cells Using Immunotargeted Nanoparticles
Author :
Crow, Matthew ; Curry, Adam ; Wax, Adam
Author_Institution :
Duke Univ., Durham
Abstract :
Using molecular imaging of immunolabeled plasmonic nanoparticles bound by cell surface receptors, we compare epidermal growth factor receptor expression, an indicator of cancerous activity, of both human epithelial carcinoma and brain tumor cell lines.
Keywords :
biomedical optical imaging; brain; cellular biophysics; molecular biophysics; nanobiotechnology; nanoparticles; plasmonics; proteins; tumours; EGFR expression; brain tumor cell lines; cell surface receptors; epidermal growth factor receptor expression; human epithelial carcinoma; immunolabeled plasmonic nanoparticles; live cancer cells; molecular imaging; Cancer; Immune system; Light scattering; Lighting; Molecular imaging; Nanoparticles; Optical scattering; Particle scattering; Spectroscopy; Tumors;
Conference_Titel :
Lasers and Electro-Optics, 2007. CLEO 2007. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-834-6
DOI :
10.1109/CLEO.2007.4452483
