Title :
Control and modeling of drug delivery devices for the treatment of diabetes
Author :
Doyle, Francis J., III ; Dorski, Christie ; Harting, Jennifer E. ; Peppas, Nikolaos A.
Author_Institution :
Sch. of Chem. Eng., Purdue Univ., West Lafayette, IN, USA
Abstract :
The complications of diabetes are thought to arise from poor control of blood glucose concentration because of inadequate secretion of insulin by the pancreas. This has motivated the undertaking of novel therapeutic approaches to improve insulin delivery. In this paper, two approaches are presented: model-based control algorithms for use in implantable insulin pumps, and a novel polymeric device which releases insulin at desirable levels
Keywords :
biomedical equipment; patient treatment; blood glucose concentration control; diabetes; drug delivery devices; implantable insulin pumps; model-based control algorithms; polymeric device; Blood; Diabetes; Drug delivery; Insulin; Mathematical model; Open loop systems; Optimal control; Pancreas; Polymers; Sugar;
Conference_Titel :
American Control Conference, Proceedings of the 1995
Conference_Location :
Seattle, WA
Print_ISBN :
0-7803-2445-5
DOI :
10.1109/ACC.1995.529356
