Title :
A highly manufacturable nano-metallic particle based DNA micro-array
Author :
Li, Jiong ; Xu, Chen ; Wang, Yijin ; Peng, Huajun ; Lu, Zuhong ; Chan, Mansun
Author_Institution :
Dept. of Electr. & Electron. Eng., Hong Kong Univ. of Sci. & Technol., China
Abstract :
A fully CMOS compatible DNA microarray system with a nanoparticle labeling protocol is demonstrated using a standard 0.5 micron CMOS process. The system has the advantages such as full CMOS capability with on-chip control circuit, very high sensitivity and ease of use without the need of expensive external optics.
Keywords :
CMOS image sensors; DNA; biomedical imaging; biomolecular electronics; microsensors; nanoparticles; 0.5 micron; CMOS compatibility; DNA microarray; genetic information; nanometallic particle; nanoparticle labeling protocol; on-chip control circuit; CMOS process; Circuits; Control systems; DNA; Labeling; Manufacturing; Optical control; Optical sensors; Protocols; System-on-a-chip;
Conference_Titel :
Electron Devices Meeting, 2004. IEDM Technical Digest. IEEE International
Print_ISBN :
0-7803-8684-1
DOI :
10.1109/IEDM.2004.1419358