Title :
MRI Template and Atlas Toolbox for the C57BL/6J Mouse Brain
Author :
Lin, Lan ; Chen, Kewei ; Valla, Jonathan ; He, Jiping ; Reiman, Eric M. ; Galons, Jean-Philippe ; Wegrzyniak, Beatrice Hauss- ; Alexander, Gene E.
Abstract :
In order to compare brain-imaging measurements from different subjects, brain-mapping algorithms are commonly used to register individual brain onto a standardized brain atlas. In this study, SPM99 was used to linearly and nonlinearly coregister a spatially standardized T2-weighted template of C57BL/6J to the atlas by Paxinos and Franklin (2001), local accuracy of between atlas and template was evaluated, and a toolbox was developed. This study provides a foundation for the region of interest analysis for mouse brain images
Keywords :
biomedical MRI; brain; medical computing; neurophysiology; C57BL/6J mouse brain; MRI template; T2-weighted template; atlas toolbox; brain atlas; brain-imaging measurements; brain-mapping algorithms; mouse brain images; Anatomy; Animals; Brain; Couplings; Helium; Histograms; Humans; Image analysis; Magnetic resonance imaging; Mice;
Conference_Titel :
Neural Engineering, 2005. Conference Proceedings. 2nd International IEEE EMBS Conference on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7803-8710-4
DOI :
10.1109/CNE.2005.1419537