• DocumentCode
    3009656
  • Title

    A simplified probing controller for glucose feeding in Escherichia coli cultivations

  • Author

    Åkesson, Mats ; Hagander, Per

  • Author_Institution
    Dept. of Autom. Control, Lund Inst. of Technol., Sweden
  • Volume
    5
  • fYear
    2000
  • fDate
    2000
  • Firstpage
    4520
  • Abstract
    A strategy for control of the glucose feed rate in cultivations of E. coli is discussed. By making probing pulses in the feed rate it is possible to detect and avoid a characteristic saturation linked to undesirable by-product formation. A simplification of a previous algorithm is presented and analyzed
  • Keywords
    biotechnology; chemical variables control; closed loop systems; feedback; process control; stability; E. coli; Escherichia coli cultivations; characteristic saturation; glucose feed rate; glucose feeding; probing pulses; simplified probing controller; Algorithm design and analysis; Automatic control; DNA; Feeds; Mass production; Microorganisms; Organisms; Probes; Proteins; Sugar;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Decision and Control, 2000. Proceedings of the 39th IEEE Conference on
  • Conference_Location
    Sydney, NSW
  • ISSN
    0191-2216
  • Print_ISBN
    0-7803-6638-7
  • Type

    conf

  • DOI
    10.1109/CDC.2001.914623
  • Filename
    914623