Title :
Synthesis of glutathione-coated quantum dots
Author :
Chomoucká, Jana ; Drbohlavová, Jana ; Adam, V. ; Kizek, Rene ; Hubalek, Jaromir
Author_Institution :
Dept. of Microelectron., Brno Univ. of Technol., Brno, Czech Republic
Abstract :
This paper is focused on the preparation and characterization of glutathione (GSH) coated near infrared quantum dots (QDs). The preparation method is based on surface modification of hydrophobic core/shell CdSeTe/CdS by glutathione, which makes the QDs water-soluble. Moreover, tripeptide GSH provides a biocompatible barrier against toxic cadmium ions of QDs core. These GSH-coated NIR QDs are suitable for in vivo imaging.
Keywords :
II-VI semiconductors; biochemistry; cadmium compounds; fluorescence; materials preparation; molecular biophysics; proteins; selenium compounds; semiconductor quantum dots; CdSeTe-CdS; GSH; bioconjugate technique; fluorescence; glutathione-coated near infrared quantum dots; hydrophobic core-shell; materials synthesis; toxic cadmium ions; tripeptide; water; Biomedical imaging; Chemical technology; Chemistry; Fluorescence; In vitro; In vivo; Neoplasms; Optical imaging; Quantum dots; Solvents;
Conference_Titel :
Electronics Technology, 2009. ISSE 2009. 32nd International Spring Seminar on
Conference_Location :
Brno
Print_ISBN :
978-1-4244-4260-7
DOI :
10.1109/ISSE.2009.5206958
