Title :
Three-Dimensional in vivo Reflectance and Fluorescence Imaging by a Handheld Dual-Axes Confocal Microscope
Author :
Ra, H. ; Piyawattanametha, W. ; Mandella, M.J. ; Liu, J. T C ; Wong, L.K. ; Wang, T.D. ; Contag, C.H. ; Kino, G.S. ; Solgaard, O.
Author_Institution :
Stanford Univ., Stanford
Abstract :
We demonstrate reflectance and fluorescence imaging with a handheld dual-axes confocal microscope based on a two-dimensional microelectromechanical system scanner. Three-dimensional imaging capability is shown in tissue, and in vivo imaging of a mouse is performed.
Keywords :
micromechanical devices; optical microscopes; optical scanners; reflectivity; 2D microelectromechanical system scanner; 3D imaging; 3D in vivo fluorescence imaging; 3D in vivo reflectance imaging; dual-axes confocal microscope; handheld microscope; mouse; Biomedical optical imaging; Fluorescence; High-resolution imaging; Humans; In vivo; Micromechanical devices; Optical imaging; Optical microscopy; Optical sensors; Reflectivity;
Conference_Titel :
Lasers and Electro-Optics, 2007. CLEO 2007. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-834-6
DOI :
10.1109/CLEO.2007.4452961