Title :
In vivo Molecular-Resonant Third Harmonic Generation Microscopy of Hemoglobin
Author :
Shih-Peng Tai ; Che-Hang Yu ; Tze-Ming Liu ; Yu-Chieh Wen
Author_Institution :
Nat. Taiwan Univ., Taipei
Abstract :
Through molecular-resonant third-harmonic-generation (THG) in hemoglobin, in vivo molecular THG microscopy of erythrocytes can be realized without using fluorescence and exogenous contrast agents. Studies in live hamster oral cavity indicate its superiority to image angiogenesis.
Keywords :
biological techniques; blood; cellular biophysics; molecular biophysics; optical harmonic generation; optical microscopy; proteins; erythrocytes; hamster oral cavity; hemoglobin; in vivo microscopy; molecular-resonant microscopy; third harmonic generation; Absorption; Biomedical optical imaging; Frequency conversion; In vivo; Nonlinear optics; Optical harmonic generation; Optical microscopy; Optical refraction; Resonance; Wavelength measurement;
Conference_Titel :
Lasers and Electro-Optics, 2007. CLEO 2007. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-834-6
DOI :
10.1109/CLEO.2007.4452971
