Auditory P300 Differences Between Healthy and Schizophrenic Subjects Revealed by Single Trial Analysis

Author

Bonala, Bharat ; Kota, Prashant ; Sundaresan, Karthik ; Boutros, Nashaat N. ; Jansen, B.H.

Author_Institution

Dept of Electr. & Comput. Eng., Houston Univ., TX

fYear

2005

fDate

16-19 March 2005

Firstpage

577

Lastpage

578

Abstract

Single trial analysis was performed to investigate the nature of the previously-reported P300 amplitude differences between normal and schizophrenic subjects. A matched filtering procedure was developed to estimate the amplitude and latency of the P300 in single trials, elicited using an auditory oddball paradigm. We found that fewer oddball stimuli produced a P300 in schizophrenia subjects than in normal subjects, and that normal subjects produced a P300 with larger amplitude. Also, the latency was larger for the schizophrenia group

Keywords

auditory evoked potentials; diseases; electroencephalography; matched filters; medical signal processing; auditory P300 differences; auditory oddball paradigm; healthy subjects; latency; matched filtering; schizophrenic subjects; single trial analysis; Amplitude estimation; Delay; Electrodes; Enterprise resource planning; Filtering; Frequency; Laboratories; Matched filters; Performance analysis; Scalp;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering, 2005. Conference Proceedings. 2nd International IEEE EMBS Conference on

Conference_Location

Arlington, VA

Print_ISBN

0-7803-8710-4

Type

conf

DOI

10.1109/CNE.2005.1419689

Filename

1419689