Title :
The Role of Amplitude and Phase in Fluorescence Coherence Imaging: From Wide Field to Nanometer Depth Profiling
Author :
Bilenca, A. ; Joo, C. ; Ozcan, A. ; De Boer, J.F. ; Bouma, B. ; Tearney, G.
Author_Institution :
Massachusetts Gen. Hosp., Boston
Abstract :
We investigate the amplitude and phase of fluorescence self-interference fields and their implication for new imaging strategies. Wide-field (y > 1 mm, z > 100 mum) high resolution (micron-scale) imaging and phase-contrast profiling with nanometer sensitivity are demonstrated.
Keywords :
biomedical optical imaging; fluorescence; image resolution; optical tomography; biomedical optical imaging; fluorescence coherence imaging; nanometer depth profiling; nanometer sensitivity; optical tomogram; phase-contrast profiling; self-interference fields; wide-field high-resolution imaging; Biomedical imaging; Biomedical optical imaging; Fluorescence; High-resolution imaging; Microscopy; Nanobioscience; Optical imaging; Optical interferometry; Optical sensors; Tomography;
Conference_Titel :
Lasers and Electro-Optics, 2007. CLEO 2007. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-834-6
DOI :
10.1109/CLEO.2007.4453093