• DocumentCode
    3016650
  • Title

    Ultrasensitive electronic detection of DNA using Si nanograting FETs coated with PNA probes

  • Author

    Regonda, Suresh ; Spurgin, Lisa ; Hu, Wenfeng

  • Author_Institution
    Global Foundries Inc., NY, USA
  • fYear
    2013
  • fDate
    5-8 Aug. 2013
  • Firstpage
    513
  • Lastpage
    516
  • Abstract
    We report the label-free rapid detection of single stranded DNA segments using lithographic Si nanograting (NG) FET devices coated with single stranded PNA probes. The NGFETs shows improved signal to noise ratio and similar sensitivity in comparison with the single nanowire FETs fabricated on the same chip. The limit of detection of our finFETs reaches sub-femtoMolar. The same devices do not respond significantly to high concentrations of non-complementary DNA segments.
  • Keywords
    DNA; MOSFET; biosensors; elemental semiconductors; nanoelectronics; nanosensors; nanowires; polymers; silicon; PNA probes; Si; finFETs; label free rapid detection; lithographic nanograting FET devices; single stranded DNA segments; ultrasensitive electronic detection; DNA; Field effect transistors; Nanobioscience; Probes; Sensors; Signal to noise ratio; Silicon;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nanotechnology (IEEE-NANO), 2013 13th IEEE Conference on
  • Conference_Location
    Beijing
  • ISSN
    1944-9399
  • Print_ISBN
    978-1-4799-0675-8
  • Type

    conf

  • DOI
    10.1109/NANO.2013.6720911
  • Filename
    6720911
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3016650