Title :
Nano-interrogation of a lipid shelled microbubble
Author :
Sboros, V. ; Glynos, E. ; Pelekasis, N. ; Koutsos, V.
Author_Institution :
Sch. of Clinical Sci. & Community Health, Univ. of Edinburgh, Edinburgh
Abstract :
Accurate stiffness measurements on the lipid MB BR14 are possible with Atomic Force Microscopy. No dependence of stiffness to MB size was found, but further measurements are required to assess this. The MB shell Young modulus extracted with a simple model disagreed with other findings, and a new structural model is required to test the contribution of the gas in the MB stiffness.
Keywords :
Young´s modulus; atomic force microscopy; bioacoustics; biomechanics; biomedical ultrasonics; biomembranes; bubbles; elastic constants; lipid bilayers; ultrasonic imaging; MB BR14 lipid; Young modulus; atomic force microscopy; lipid shelled microbubble; microbubble structural model; stiffness measurements; Atomic force microscopy; Biomedical measurements; Elasticity; Force measurement; Lipidomics; Mechanical factors; Reproducibility of results; Size measurement; Springs; Viscosity;
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0241
