Title :
A surface acoustic wave sensor for detection of cell adhesion
Author :
Guhr, Glen ; Brünig, Raimund ; Jäger, Martin ; Poll, Rüdiger ; Schmidt, Hagen ; Weihnacht, Manfred
Author_Institution :
Solid State & Mater. Res. Dresden, Leibniz Inst., Dresden
Abstract :
In this paper preliminary results for the detection of the cell adhesion process with shear-horizontal polarized surface acoustic wave devices (SH-SAW) are presented. The murine fibroblast cell line L929 was investigated. Therefore a special measurement setup was developed. It enables us to perform long term measurements at stable ambient conditions. Different amounts of cells where seeded. According to the number of cells different slopes of resonant frequency increase vs. time were found.
Keywords :
adhesion; biosensors; cellular biophysics; surface acoustic wave sensors; cell adhesion process detection; cell-based biosensor; murine fibroblast cell line L929; resonant frequency; shear-horizontal polarized SAW devices; surface acoustic wave devices; surface acoustic wave sensor; Acoustic measurements; Acoustic sensors; Acoustic signal detection; Acoustic waves; Adhesives; Fibroblasts; Performance evaluation; Polarization; Surface acoustic wave devices; Surface acoustic waves; L929; cell adhesion; cell based biosensor; surface acoustic wave (SAW);
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0480
