DocumentCode :
3025541
Title :
A mathematical model simulating disease treatment: S.L.E.
Author :
Merrill, S.J.
Author_Institution :
Marquette University, Milwaukee, Wisconsin
fYear :
1979
fDate :
10-12 Jan. 1979
Firstpage :
750
Lastpage :
754
Abstract :
A model of B-lymphocyte stimulation and associated antibody production is used to simulate treatment and the course of Systematic lupus erythematosis (SLE). Some of the most severe symptoms of the disease are thought to be consequences of the production of antibody against our own DNA(SLE is an "autoimmune" disease). Treatment consists of minimizing organ damage by suppressing the production of antibody (by suppressing all the components of the immune response) and maintaining the patient in a stable condition. The effect of treatment in use and the existence of a stable equilibrium is demonstrated in the model.
Keywords :
Continuous production; Diseases; Mathematical model; Proteins; Statistics;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Decision and Control including the 17th Symposium on Adaptive Processes, 1978 IEEE Conference on
Conference_Location :
San Diego, CA, USA
Type :
conf
DOI :
10.1109/CDC.1978.268026
Filename :
4046213
Link To Document :
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