Title :
Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering
Author :
Mathew, Jeena Ann ; Kache, Vikas ; Liu, Chao ; Tang, Liping ; Yang, Jian
Author_Institution :
Univ. of Texas at Arlington, Arlington
Abstract :
The lack of suitable scaffolding materials and viable scaffold design is challenging the success of tissue engineering. In the present study, we developed a new scaffolding strategy using a secondary porogen, poly(ethylene glycol) dimethyl ether along with sieved salts based on traditional salt-leaching method. This new scaffolding technology could allow us to fabricate nano- featured highly interconnective macroporous biodegradable elastic scaffolds based on a newly developed crosslinked poly(l,8-octanediol citrate) (POC) for cardiovascular tissue engineering.
Keywords :
biodegradable materials; cardiovascular system; elastic constants; leaching; nanobiotechnology; porous materials; tissue engineering; biodegradable materials; cardiovascular tissue engineering; crosslinked poly(1,8-octanediol citrate); nanofeatured-highly-interconnective macroporous elastic scaffolds; poly(ethylene glycol) dimethyl ether; salt-leaching method; secondary porogen; sieved salts; Biodegradable materials; Biological materials; Biomedical engineering; Blood vessels; Cardiology; Chaos; Nanobioscience; Regeneration engineering; Solvents; Tissue engineering;
Conference_Titel :
Engineering in Medicine and Biology Workshop, 2007 IEEE Dallas
Conference_Location :
Dallas, TX
Print_ISBN :
978-1-4244-1626-4
DOI :
10.1109/EMBSW.2007.4454169
