Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering

Author

Mathew, Jeena Ann ; Kache, Vikas ; Liu, Chao ; Tang, Liping ; Yang, Jian

Author_Institution

Univ. of Texas at Arlington, Arlington

fYear

2007

fDate

11-12 Nov. 2007

Firstpage

43

Lastpage

46

Abstract

The lack of suitable scaffolding materials and viable scaffold design is challenging the success of tissue engineering. In the present study, we developed a new scaffolding strategy using a secondary porogen, poly(ethylene glycol) dimethyl ether along with sieved salts based on traditional salt-leaching method. This new scaffolding technology could allow us to fabricate nano- featured highly interconnective macroporous biodegradable elastic scaffolds based on a newly developed crosslinked poly(l,8-octanediol citrate) (POC) for cardiovascular tissue engineering.

Keywords

biodegradable materials; cardiovascular system; elastic constants; leaching; nanobiotechnology; porous materials; tissue engineering; biodegradable materials; cardiovascular tissue engineering; crosslinked poly(1,8-octanediol citrate); nanofeatured-highly-interconnective macroporous elastic scaffolds; poly(ethylene glycol) dimethyl ether; salt-leaching method; secondary porogen; sieved salts; Biodegradable materials; Biological materials; Biomedical engineering; Blood vessels; Cardiology; Chaos; Nanobioscience; Regeneration engineering; Solvents; Tissue engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Workshop, 2007 IEEE Dallas

Conference_Location

Dallas, TX

Print_ISBN

978-1-4244-1626-4

Type

conf

DOI

10.1109/EMBSW.2007.4454169

Filename

4454169