BIO101 - EST sequence management and annotation system

Author

Lee, In-Yee ; Lin, Wen-Chang ; Ho, Jan-Ming ; Wang, Gu-Liang ; Chen, Ming-Syan

Author_Institution

Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei

fYear

2005

fDate

21-21 Dec. 2005

Firstpage

40

Lastpage

45

Abstract

Laboratories worldwide are working on EST cDNA library and microarray projects, each project involving hundreds to hundreds of thousands of clones. To support the needs of individual laboratories, an efficient EST sequence management system is needed. Here, we describe BIO101, a centralized approach to laboratory EST sequence management and functional annotation. The system includes a) laboratory-based authorization, project-focused and custom database management features; b) a pipeline with integrated tools for producing and clustering high-quality ESTs and for identifying homologues; c) a pipeline scheduling mechanism that emphasizes fairness; and d) collaborative manual and automatic functional annotation features. BIO101 is accessible to registered members at http://bio101.iis.sinica.edu.tw/

Keywords

DNA; biology computing; biomedical engineering; database management systems; genetic engineering; molecular biophysics; scheduling; BIO101; EST annotation system; EST cDNA library; EST sequence management; custom database management; expressed sequence tags; laboratory-based authorization; nucleotide sequences; pipeline scheduling mechanism; project-focused database management; Automation; Cloning; DNA; Laboratories; Libraries; Organisms; Pipelines; Project management; Scheduling; Sequences;

fLanguage

English

Publisher

ieee

Conference_Titel

Signal Processing and Information Technology, 2005. Proceedings of the Fifth IEEE International Symposium on

Conference_Location

Athens

Print_ISBN

0-7803-9313-9

Type

conf

DOI

10.1109/ISSPIT.2005.1577067

Filename

1577067