Title :
A fluorescence imaging system for oral cancer and precancer detection
Author :
Wang, Chih-Yu ; Tsai, Tsuimin ; Chen, Chin-Tin ; Chiang, Ching-Fen ; Hsin-Ming Chen ; Chiang, Chun-Pin
Author_Institution :
Dept. of Biomed. Eng., I-Shou Univ., Kaohsiung, Taiwan
Abstract :
A fluorescence imaging system was constructed to take images of oral cavity for oral cancer and precancer detection. Being applied at oral cavity for one hour, ALA would be metabolized by cells to be PpIX, which emitted red fluorescence (630 nm) while illuminated by violet light (wavelength 410 nm). The results show that explicit red color was presented at those cancerous/precancerous areas on the image. The abnormal area could be easily identified. This imaging technique is potential for oral cancer/precancer diagnosis.
Keywords :
bio-optics; biomedical equipment; biomedical optical imaging; cancer; cellular biophysics; fluorescence; 1 hour; 410 nm; 630 nm; fluorescence imaging system; oral cancer; oral cancer/precancer diagnosis; precancer detection; red fluorescence; Biomedical engineering; Biomedical imaging; Cancer detection; Dentistry; Fluorescence; Laser excitation; Light sources; Medical diagnostic imaging; Medical treatment; Telescopes;
Conference_Titel :
Biomedical Engineering, 2003. IEEE EMBS Asian-Pacific Conference on
Print_ISBN :
0-7803-7943-8
DOI :
10.1109/APBME.2003.1302629