• DocumentCode
    3038017
  • Title

    Simplified measurement of histamine H1 receptor in human brains with PET

  • Author

    Mochizuki, Hideki ; Kimura, Yuichi ; Ishii, Kenji ; Oda, Keiichi ; Sasaki, Toru ; Tashiro, Manabu ; Yanai, Kazuhiko ; Ishiwata, Kiichi

  • Author_Institution
    Dept. of Pharmacology, Tohoku Univ. Sch. of Med., Sendai, Japan
  • fYear
    2003
  • fDate
    20-22 Oct. 2003
  • Firstpage
    198
  • Lastpage
    199
  • Abstract
    In the present study, we developed a simplified positron emission tomography (PET) measurement to evaluate histamine H1 receptor (HIR). Our findings demonstrated that brain images reflecting HIR can be obtained with static PET scan started from 70 min after injection of [11C]doxepin.
  • Keywords
    biomedical measurement; brain; organic compounds; positron emission tomography; 17 min; PET; [11C]doxepin; brain images; histamine H1 receptor; human brains; receptor imaging; simplified measurement; simplified positron emission tomography measurement; Blood; Brain modeling; Curve fitting; Data acquisition; Density measurement; Humans; Linearity; Newton method; Positron emission tomography; Timing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering, 2003. IEEE EMBS Asian-Pacific Conference on
  • Print_ISBN
    0-7803-7943-8
  • Type

    conf

  • DOI
    10.1109/APBME.2003.1302652
  • Filename
    1302652