DocumentCode :
3038017
Title :
Simplified measurement of histamine H1 receptor in human brains with PET
Author :
Mochizuki, Hideki ; Kimura, Yuichi ; Ishii, Kenji ; Oda, Keiichi ; Sasaki, Toru ; Tashiro, Manabu ; Yanai, Kazuhiko ; Ishiwata, Kiichi
Author_Institution :
Dept. of Pharmacology, Tohoku Univ. Sch. of Med., Sendai, Japan
fYear :
2003
fDate :
20-22 Oct. 2003
Firstpage :
198
Lastpage :
199
Abstract :
In the present study, we developed a simplified positron emission tomography (PET) measurement to evaluate histamine H1 receptor (HIR). Our findings demonstrated that brain images reflecting HIR can be obtained with static PET scan started from 70 min after injection of [11C]doxepin.
Keywords :
biomedical measurement; brain; organic compounds; positron emission tomography; 17 min; PET; [11C]doxepin; brain images; histamine H1 receptor; human brains; receptor imaging; simplified measurement; simplified positron emission tomography measurement; Blood; Brain modeling; Curve fitting; Data acquisition; Density measurement; Humans; Linearity; Newton method; Positron emission tomography; Timing;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Engineering, 2003. IEEE EMBS Asian-Pacific Conference on
Print_ISBN :
0-7803-7943-8
Type :
conf
DOI :
10.1109/APBME.2003.1302652
Filename :
1302652
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=3038017
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