Title :
Experimental demonstration and analysis of DNA passage in nanopore-based nanofluidic transistors
Author :
Paik, Kee-Hyun ; Liu, Yang ; Tabard-Cossa, Vincent ; Huber, David E. ; Provine, J. ; Howe, Roger T. ; Davis, Ronald W. ; Dutton, Robert W.
Author_Institution :
Dept. of Electr. Eng., Stanford Univ., Stanford, CA, USA
Abstract :
We investigate DNA passage through a nanofluidic transistor (NFT) composed of large diameter nanopores (~200nm) with an embedded metal gate. The nanopores are large enough to be made by currently available photolithography process for manufacturability. We observe that the NFT is capable of electrostatic control of DNA capture rate, the equivalent of current in the electron transistor, with similar operating principle as their electron device counterpart.
Keywords :
DNA; MOSFET; electrostatics; nanofluidics; photolithography; DNA capture rate; DNA passage; electron transistor; electrostatic control; embedded metal gate; large diameter nanopores; nanopore-based nanofluidic transistors; photolithography; Aluminum oxide; Arrays; DNA; Electrodes; Fluids; Logic gates; Transistors;
Conference_Titel :
Electron Devices Meeting (IEDM), 2011 IEEE International
Conference_Location :
Washington, DC
Print_ISBN :
978-1-4577-0506-9
Electronic_ISBN :
0163-1918
DOI :
10.1109/IEDM.2011.6131646