Systems Biology Platform for Mechanism Clarification of TCM

Author

Wang, Yun ; Hao, JinLing ; Qiao, Yanjiang

Author_Institution

Sch. of Chinese Pharmacy, Beijing Univ. of Chinese Med., Beijing, China

Volume

3

fYear

2009

fDate

19-21 May 2009

Firstpage

385

Lastpage

389

Abstract

According to the mechanism clarification problem of traditional Chinese medicine (TCM), a systems biology platform was constructed using the related achievements as the basis, entity grammar systems as the framework and database construction, data mining, qualitative reasoning as the kernel techniques. This platform is composed of TCM active components database, TCM prescription database, drug targets database, biological molecular interaction network database, reasoning engine and user interface. After the TCM prescription is selected, the mechanism model can be generated automatically by the platform, which can be used to further study of TCM. This work will contribute to the modernization of Chinese medicine.

Keywords

biology computing; common-sense reasoning; data mining; database management systems; drugs; grammars; medicine; user interfaces; TCM active components database; TCM prescription database; biological molecular interaction network database; data mining; database construction; drug targets database; entity grammar systems; kernel techniques; mechanism clarification; qualitative reasoning; reasoning engine; systems biology platform; traditional Chinese medicine; user interface; Biological system modeling; Chemicals; Data mining; Deductive databases; Drugs; Engines; Intelligent systems; Kernel; Systems biology; User interfaces;

fLanguage

English

Publisher

ieee

Conference_Titel

Intelligent Systems, 2009. GCIS '09. WRI Global Congress on

Conference_Location

Xiamen

Print_ISBN

978-0-7695-3571-5

Type

conf

DOI

10.1109/GCIS.2009.368

Filename

5209122