Wettability Switching Technique of a Biocompatible Polymer

Author

Takahashi, Y. ; Teh, K.S. ; Lu, Y.W.

Author_Institution

Rochester Inst. of Technol., Rochester, NY

fYear

2009

fDate

25-29 Jan. 2009

Firstpage

459

Lastpage

462

Abstract

In this paper we present data of protein adsorption on topographically altered active polymeric films, investigated using atomic force microscopy (AFM), fluorescence microscopy, and contact angle measurement. The surface wettability of biocompatible polypyrrole (PPy) films was altered via low applied currents, and we have demonstrated switchable hydrophobic-hydrophilic surfaces, used as protein adhesion substrates. The preliminary results showed that both BSA and fibronectin have higher affinities for and adhere preferentially to hydrophobic surfaces.

Keywords

adhesion; atomic force microscopy; biomedical materials; biomedical optical imaging; contact angle; fluorescence spectroscopy; molecular biophysics; polymer films; proteins; wetting; AFM; atomic force microscopy; bio-MEMS; biocompatible polymer; biocompatible polypyrrole films; contact angle measurement; fibronectin; fluorescence microscopy; hydrophobic-hydrophilic surfaces; protein adhesion substrate; protein adsorption; surface wettability; topographically altered active polymeric films; wettability switching; Adhesives; Atomic force microscopy; Electric potential; Nanobioscience; Nanostructures; Polymer films; Proteins; Rough surfaces; Surface roughness; Surface topography;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems, 2009. MEMS 2009. IEEE 22nd International Conference on

Conference_Location

Sorrento

ISSN

1084-6999

Print_ISBN

978-1-4244-2977-6

Electronic_ISBN

1084-6999

Type

conf

DOI

10.1109/MEMSYS.2009.4805418

Filename

4805418