Title : 
A low-cost reliable online noise level estimation for accurate spike detection in extracellular recordings
         
        
            Author : 
Artan, N.S. ; Xiaoxiang Xu ; Chao, H. Jonathan
         
        
            Author_Institution : 
Dept. of Electr. & Comput. Eng., Polytech. Inst. of New York Univ., Brooklyn, OH, USA
         
        
        
        
        
        
            Abstract : 
On-line unsupervised spike detection is a fundamental building block for autonomous neural implants. To accurately monitor neurological activity, the spike detectors should be able to operate at a wide range of firing rates. This can only be achieved by a careful estimation of instantaneous noise level in the recording. In this paper, we propose a system for estimating noise level in extracellular recordings, which is reliable across a wide range of firing rates, and thus leads to accurate spike detection.
         
        
            Keywords : 
cellular biophysics; medical signal detection; medical signal processing; neurophysiology; prosthetics; signal denoising; autonomous neural implants; extracellular recordings; firing rates; instantaneous noise level estimation; neurological activity monitoring; online noise level estimation; spike detection; spike detectors; Accuracy; Complexity theory; Estimation; Firing; Noise level; Signal to noise ratio;
         
        
        
        
            Conference_Titel : 
Biomedical Circuits and Systems Conference (BioCAS), 2012 IEEE
         
        
            Conference_Location : 
Hsinchu
         
        
            Print_ISBN : 
978-1-4673-2291-1
         
        
            Electronic_ISBN : 
978-1-4673-2292-8
         
        
        
            DOI : 
10.1109/BioCAS.2012.6418458