• DocumentCode
    3048083
  • Title

    A Populations Evolution Study Using the Genotype Frequency Data of Single Nucleotide Polymorphism from Y-Chromosome

  • Author

    Pei, Zhili ; Kong, Ying ; Shi, Xiaohu ; Lian, Zhichao ; Tang, Xuning ; Liu, Lisha ; Cao, Zhongbo ; Liang, Yanchun

  • Author_Institution
    Key Lab. of Symbol Comput. & Knowledge Eng. of the Minist. of Educ., Jilin Univ., Changchun
  • fYear
    2007
  • fDate
    6-8 July 2007
  • Firstpage
    290
  • Lastpage
    293
  • Abstract
    This paper proposes a novel way for the population evolution research. In the paper, it constructs the phylogenies tree of four populations using the single nucleotide polymorphism (SNP) genotype frequency of human´s Y- chromosome provided by the international Hapmap project firstly, then a mathematical model is proposed to calculate the distance of any two races for all SNP genotype frequency. The simulation results suggest that the theory of constructing phylogenetic tree by analyzing SNP genotype frequency is effective. The accuracy of the adopted processing method is also shown by the simulation results. About the origination of modern human being, the result of this study can support the ´out of Africa´ hypothesis, and this result is same as most evidences of paleontology.
  • Keywords
    cellular biophysics; genetics; palaeontology; polymorphism; genotype frequency; genotype frequency data; human Y-chromosome; international Hapmap project; modern human being; paleontology; phylogeny tree; single nucleotide polymorphism; Africa; Analytical models; Computer science; DNA; Evolution (biology); Frequency; Genetics; Humans; Mathematical model; Phylogeny;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
  • Conference_Location
    Wuhan
  • Print_ISBN
    1-4244-1120-3
  • Type

    conf

  • DOI
    10.1109/ICBBE.2007.78
  • Filename
    4272562