DocumentCode
3048460
Title
An Algorithm Based on Fast Walsh Transform for Multiple Sequence Alignment
Author
Huang, Beibei ; Guo, Zonglin ; Cao, Xiaojing
Author_Institution
State Key Lab. of Software Eng., Wuhan Univ., Wuhan
fYear
2007
fDate
6-8 July 2007
Firstpage
374
Lastpage
377
Abstract
As a NPproblem, multiple sequence alignment is solved mainly in approximative or heuristic methods, most of which are based on dynamic programming algorithm raised by Smith-Waterman in 1981. In this paper, an alignment method based on fast Walsh transform by the means of Identification of molecular subsequences is brought forward, and it adopts triplet code and subsection strategy. The method increases the differentiation through adding more vectors, it increases the precision and reduces the complexity, and Star-Alignment is introduced to make pair alignment into the alignment. Experiments show the algorithm is effective.
Keywords
biology computing; molecular biophysics; fast Walsh transform; molecular subsequences identification; multiple sequence alignment; star-alignment; Amino acids; Dynamic programming; Educational institutions; Heuristic algorithms; Laboratories; Mathematical model; Mathematics; Software algorithms; Software engineering; Software packages;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location
Wuhan
Print_ISBN
1-4244-1120-3
Type
conf
DOI
10.1109/ICBBE.2007.99
Filename
4272583
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