DocumentCode :
3048460
Title :
An Algorithm Based on Fast Walsh Transform for Multiple Sequence Alignment
Author :
Huang, Beibei ; Guo, Zonglin ; Cao, Xiaojing
Author_Institution :
State Key Lab. of Software Eng., Wuhan Univ., Wuhan
fYear :
2007
fDate :
6-8 July 2007
Firstpage :
374
Lastpage :
377
Abstract :
As a NPproblem, multiple sequence alignment is solved mainly in approximative or heuristic methods, most of which are based on dynamic programming algorithm raised by Smith-Waterman in 1981. In this paper, an alignment method based on fast Walsh transform by the means of Identification of molecular subsequences is brought forward, and it adopts triplet code and subsection strategy. The method increases the differentiation through adding more vectors, it increases the precision and reduces the complexity, and Star-Alignment is introduced to make pair alignment into the alignment. Experiments show the algorithm is effective.
Keywords :
biology computing; molecular biophysics; fast Walsh transform; molecular subsequences identification; multiple sequence alignment; star-alignment; Amino acids; Dynamic programming; Educational institutions; Heuristic algorithms; Laboratories; Mathematical model; Mathematics; Software algorithms; Software engineering; Software packages;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
Type :
conf
DOI :
10.1109/ICBBE.2007.99
Filename :
4272583
Link To Document :
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