Bacteria-Assisted Photothermal Therapy in Cancers Cells

Photothermal therapy by the strategy of adding Au nanoparticles (NPs), UV-absorbed around near IR range of 800-1000 nm, had been studied and used as a novel tool to eliminate and kill cancer cells. However, we had successfully developed the bacteria of E. Coli. as a new template for growing and self-assembling Au NPs even nano-shell on E. Coli. surface and treated cells for photothermal therapy studies. And we not only found the E. Coli. coated with Au NPs were curative effect to cancer cells using photothermal therapy but also the those particles were non-toxicity to cells. Here, we had succeeded to develope the bacteria of E. Coli. as a new template for growing and self-assembling Au NPs on E. Coli. surface. We not only found the E. Coli. coated with Au NPs were curative effect to cancer cells using photothermal therapy but also the those particles were non-toxicity to cells.