Title :
Brain Interface Device for Long-Term Observation of Mouse Brain Using Two-Photon Uncaging Microscopy
Author :
Takehara, H. ; Moliri, S. ; Terakado, R. ; Akagi, T. ; Noguchi, J. ; Kasai, H. ; Ichiki, T.
Author_Institution :
Univ. of Tokyo, Tokyo
Abstract :
In this study a brain interface device for long-term two-photon microscopy observation by applying microfluidic device technology using glass or polymer materials. The device is designed to be implanted into a certain part of the skull bone to close the drilled hole, and will enable easy delivery of caged glutamate into the brain tissue without any degradation of microscopy observation.
Keywords :
bioMEMS; biomedical measurement; biomedical optical imaging; brain; microfluidics; neurophysiology; optical microscopy; prosthetics; brain interface device; brain tissue; glass; microfluidic device technology; mouse brain; polymer materials; skull bone; two-photon uncaging microscopy; Biological materials; Bones; Brain; Degradation; Glass; Mice; Microfluidics; Microscopy; Polymers; Skull;
Conference_Titel :
Microprocesses and Nanotechnology, 2007 Digest of papers
Conference_Location :
Kyoto
Print_ISBN :
978-4-9902472-4-9
DOI :
10.1109/IMNC.2007.4456329
