Simulation Study on Blood Glucose Control in Diabetics

Author

Li, Chengwei ; Hu, Ruiqiang

Author_Institution

Sch. of Electr. Eng. & Autom., Harbin Inst. of Technol., Harbin

fYear

2007

fDate

6-8 July 2007

Firstpage

1103

Lastpage

1106

Abstract

In this paper, some theoretical analysis of the control of blood glucose levels in diabetic individuals is undertaken using a simple mathematical model of the dynamics of glucose and insulin interaction in the blood system developed by Bergman et al. One is an open-loop control, which is based on the mathematical model of insulin curve. The other is a closed-loop control, which is using a classic PID controller. The aim of the control performance was assessed in terms of its ability to track a setpoint (70 mg/dl)form initial state of hyperglycemia, as well as in response to a meal disturbance. The MATLAB simulation is performed to manifest the theoretical analysis. The development reported in this paper are expected to simplify the insulin delivery mechanism, thereby enhancing the quality of life of the patient.

Keywords

blood; closed loop systems; diseases; mathematics computing; medical computing; medical control systems; open loop systems; patient treatment; sugar; three-term control; MATLAB simulation; PID controller; blood glucose control; closed-loop control; diabetics; glucose dynamics; hyperglycemia; insulin delivery mechanism; insulin interaction; mathematical model; open-loop control; Blood; Control system analysis; Diabetes; Insulation life; Insulin; MATLAB; Mathematical model; Open loop systems; Sugar; Three-term control;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on

Conference_Location

Wuhan

Print_ISBN

1-4244-1120-3

Type

conf

DOI

10.1109/ICBBE.2007.285

Filename

4272769