Title :
Hibert-Huang Transform Analysis for Neuron Signal of Microelectrode-Guided Stereotactic Neurosurgery for Parkinson´s Disease
Author :
Xue, Han ; Qian, Zhiyu
Author_Institution :
Dept. of Biomed. Eng., Nanjing Univ. of Aeronaut. & Astronaut., Nanjing
Abstract :
Electrophysiological target localization is the key technology in microelectrode-guided stereotactic neurosurgery for Parkinson´s disease (PD). A signal analysis method based on Hilbert-Huang transform (HHT) was introduced to identify target and microelectrode location. By decomposing the clinic microelectrode recording (MER) of PD into intrinsic mode functions (IMFs), and the marginal spectrums of IMFs were achieved by Hilbert transform, and the characteristic factor of brain neuron structures of microelectrode track intraoperatively was extracted. The results show that HHT can help us to distinguish operation target and brain tissue structure.
Keywords :
Hilbert transforms; bioelectric phenomena; biological tissues; biomedical electrodes; biomedical measurement; brain; diseases; surgery; Hilbert-Huang transform analysis; Parkinson´s disease; brain neuron structures; brain tissue structure; clinic microelectrode recording; electrophysiological target localization; intrinsic mode functions; microelectrode location; microelectrode-guided stereotactic neurosurgery; neuron signal; Biomedical engineering; Brain; Microelectrodes; Neurons; Neurosurgery; Parkinson´s disease; Partial discharges; Signal analysis; Signal processing; Surges;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
DOI :
10.1109/ICBBE.2007.328