Ceramide channel formed in open well thermal plastic chips

Author

Shao, Chenren ; Colombini, Marco ; DeVoe, Don L.

Author_Institution

Dept. of Mech. Eng., Univ. of Maryland, College Park, MD, USA

fYear

2009

fDate

9-11 Dec. 2009

Firstpage

1

Lastpage

2

Abstract

In this paper, we report a nanopore study platform in a microfluidic chip to gain easier control over temperature and flow conditions. Micro channels are milled with Computer Numerical Control machine on two polycarbonate wafers and then sealed into a two-chamber system by thermal bonding with a PVDC as partition. A round hole of 80-100 Â¿m in diameter was burnt by hot needle at the cross section of two channels and will hold the PPM during the experiment. Two nanoports (Upchurch, WA) holding Ag/AgCl electrodes are fixed at ends of micro channels by wax and easy to remove and re-apply.

Keywords

biomembranes; computerised numerical control; microchannel flow; seals (stoppers); Ag-AgCl; Ag/AgCl electrodes; PVDC; ceramide channel; computer numerical control machine; flow conditions; hot needle; microchannels; microfluidic chip; nanopore study platform; open well thermal plastic chips; polycarbonate wafers; size 80 mum to 100 mum; temperature conditions; thermal bonding; two-chamber system; Biomembranes; Control systems; Educational institutions; Lipidomics; Microfluidics; Nanoporous materials; Painting; Plastics; Proteins; Temperature control;

fLanguage

English

Publisher

ieee

Conference_Titel

Semiconductor Device Research Symposium, 2009. ISDRS '09. International

Conference_Location

College Park, MD

Print_ISBN

978-1-4244-6030-4

Electronic_ISBN

978-1-4244-6031-1

Type

conf

DOI

10.1109/ISDRS.2009.5378115

Filename

5378115