Title :
Lensless imaging device for digital counting of fluorescent micro-droplet chambers
Author :
Sasagawa, Kiyotaka ; Takehara, Hironari ; Miyazawa, K. ; Okabayashi, D. ; Noda, Toshio ; Tokuda, Takashi ; Kim, Seong-Ho ; Iino, Ryota ; Noji, H. ; Ohta, Jun
Author_Institution :
Grad. Sch. of Mater. Sci., Nara Inst. of Sci. & Technol., Ikoma, Japan
fDate :
June 30 2013-July 4 2013
Abstract :
We developed a miniaturized lensless fluorescence imaging device for digital counting of micro-droplet chamber array, which is used in single molecule detection. Fluorescent beads in a droplet array were imaged with the device and its resolution was improved by using deconvolution method.
Keywords :
CMOS image sensors; biomedical optical imaging; deconvolution; drops; enzymes; fluorescence; image resolution; molecular biophysics; deconvolution method; digital counting; fluorescent beads; fluorescent microdroplet chambers; image resolution; microdroplet chamber array; miniaturized lensless fluorescence imaging device; single molecule detection; Arrays; Fluorescence; Microscopy; Spatial resolution; Substrates;
Conference_Titel :
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2013 Conference on
Conference_Location :
Kyoto
DOI :
10.1109/CLEOPR.2013.6600115